Massimo Donadelli Selected Research

trichostatin A (A 300)

1/2018	Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: An in depth proteomic study.
4/2009	Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study.
7/2007	Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.
5/2007	Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A.
6/2006	Trichostatin A enhances the response of chemotherapeutic agents in inhibiting pancreatic cancer cell proliferation.
11/2005	Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A.
9/2004	Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells.
10/2003	Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells.
6/2003	Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Massimo Donadelli Research Topics

Disease

44	Neoplasms (Cancer) 06/2022 - 10/2003
22	Adenocarcinoma 12/2020 - 06/2003
14	Pancreatic Neoplasms (Pancreatic Cancer) 06/2022 - 10/2003
4	Hypoxia (Hypoxemia) 01/2021 - 02/2011
3	Carcinogenesis 01/2022 - 02/2011
3	Pancreatic Ductal Carcinoma 11/2005 - 06/2003
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2019 - 01/2019
2	Breast Neoplasms (Breast Cancer) 11/2018 - 01/2016
2	Genomic Instability 01/2016 - 01/2015
2	Neoplasm Metastasis (Metastasis) 01/2016 - 02/2011
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2021
1	Seizures (Absence Seizure) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2020
1	Osteosarcoma (Osteogenic Sarcoma) 01/2020
1	Stroke (Strokes) 01/2020
1	Inflammation (Inflammations) 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2019
1	Triple Negative Breast Neoplasms 11/2018
1	Hematologic Neoplasms (Hematological Malignancy) 03/2018
1	Hypersensitivity (Allergy) 01/2018
1	Disease Progression 01/2018

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2003
15	Pharmaceutical PreparationsIBA 06/2022 - 06/2003
12	Gemcitabine FDA Link 12/2020 - 11/2005
12	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2020 - 10/2012
9	Biomarkers (Surrogate Marker)IBA 01/2020 - 02/2011
9	trichostatin A (A 300)IBA 01/2018 - 06/2003
7	EnzymesIBA 01/2021 - 05/2014
6	AntioxidantsIBA 01/2021 - 12/2016
6	theasinensin AIBA 04/2009 - 06/2003
5	Protein Isoforms (Isoforms)IBA 01/2020 - 01/2016
5	Uncoupling Protein 2IBA 12/2017 - 10/2012
5	Histone Deacetylase InhibitorsIBA 04/2009 - 10/2003
5	Histone Deacetylases (Histone Deacetylase)IBA 07/2007 - 06/2003
4	genipinIBA 12/2017 - 10/2012
3	Liposomes (Liposome)IBA 12/2020 - 05/2013
3	Biological ProductsIBA 01/2020 - 01/2017
3	CytokinesIBA 01/2018 - 04/2008
3	Acetylcysteine (Siran)FDA LinkGeneric 12/2016 - 09/2006
3	Messenger RNA (mRNA)IBA 10/2012 - 09/2006
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2020
2	CatalaseIBA 01/2021 - 01/2018
2	Succinic Acid (Succinate)IBA 01/2020 - 01/2019
2	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2020 - 01/2019
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 11/2018
2	SestrinsIBA 09/2019 - 01/2019
2	Deoxyglucose (2 Deoxy D glucose)IBA 12/2018 - 12/2016
2	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2018 - 04/2009
2	Chloroquine (Aralen)FDA LinkGeneric 11/2018 - 03/2013
2	Everolimus FDA Link 12/2017 - 01/2016
2	MTOR InhibitorsIBA 12/2017 - 03/2015
2	ranpirnase (Pannon)IBA 11/2017 - 03/2015
2	Superoxides (Superoxide)IBA 03/2015 - 10/2012
2	MicroRNAs (MicroRNA)IBA 07/2014 - 11/2013
2	LigandsIBA 11/2013 - 05/2013
2	prolinedithiocarbamate (PDTC)IBA 04/2011 - 09/2006
2	pyrrolidine dithiocarbamic acidIBA 04/2011 - 09/2006
2	Free Radical ScavengersIBA 07/2007 - 09/2006
2	Fluorouracil (Carac)FDA LinkGeneric 06/2006 - 10/2003
2	Decitabine FDA Link 01/2005 - 12/2003
1	Conditioned Culture MediaIBA 01/2022
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 12/2020
1	Amino Acids FDA Link 12/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 12/2020
1	Glutamine (L-Glutamine)FDA Link 12/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2020
1	indolepropanol phosphate (IPP)IBA 01/2020
1	isopentenyl pyrophosphate (isopentenyl diphosphate)IBA 01/2020
1	Superoxide DismutaseIBA 01/2020
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2020
1	Sirtuin 3IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 04/2019
1	alpha-hydroxyglutarateIBA 01/2019
1	FumaratesIBA 01/2019
1	Fumarate Hydratase (Fumarase)IBA 01/2019
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2019
1	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA 12/2018
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2018
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 11/2018
1	NitritesIBA 11/2018
1	CalreticulinIBA 11/2018
1	Bortezomib (Velcade)FDA Link 11/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018
1	Drug CombinationsIBA 12/2017
1	Oxidoreductases (Dehydrogenase)IBA 12/2017
1	Glyceraldehyde 3-Phosphate (Glyceraldehyde 3 Phosphate)IBA 12/2017
1	Adenosine Triphosphatases (ATPase)IBA 12/2016
1	NADH DehydrogenaseIBA 12/2016
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 12/2016
1	oligomycin sensitivity-conferring protein (complex V)IBA 12/2016
1	TOR Serine-Threonine KinasesIBA 01/2016
1	Pyruvate KinaseIBA 01/2016
1	Synthetic DrugsIBA 01/2016

Therapy/Procedure

18	Therapeutics 06/2022 - 06/2006
8	Drug Therapy (Chemotherapy) 03/2015 - 06/2006
2	Aftercare (After-Treatment) 01/2005 - 09/2004
1	Neurological Rehabilitation 01/2020
1	Precision Medicine 09/2019